An efficient algorithm for measurement of retinal vessel diameter from fundus images based on directional filtering

摘要

Automatic measurement of vessels from fundus images is a crucial step for assessing vessel anomalies in ophthalmological community, where the change in retinal vessel diameters is believed to be indicative of the risk level of diabetic retinopa-thy. In this paper, a new retinal vessel diameter measurement method by combining vessel orientation estimation and filter response is proposed. Its interesting characteristics include: (1) different from the methods that only fit the vessel profiles, the proposed method extracts more stable and accurate vessel diameter by casting this problem as a maximal response problem of a variation of Gabor filter; (2) the proposed method can directly and efficiently estimate the vessel's orientation, which is usually captured by time-consuming multi-orientation fitting techniques in many existing methods. Experimental results shows that the proposed method both retains the computational simplicity and achieves stable and accurate estimation results.