2-[4-(2-bromoethoxy) phenoxy] ethanol(3) was prepared from p-benzyloxyphenol by a three-step reaction. 2-[4-(2-morpholino propoxy)phenoxy]ethanol(4) was prepared by the reaction of 3 with morpholine. A novel 2-[4-(3-morpholino propoxy)phenoxy] ethyl-isothiourea was successfully synthesized from 4 by chlorosulfonylation, then introducing thiourea group. The structures were characterized by ]H NMR, 13C NMR and MS.%以对苄氧基苯酚为原料,经三步反应合成了2-[4-(3-氯丙氧基)苯氧基]乙醇(3);在3中引入吗啉基团制得2-[4-(3-吗啉丙氧基)苯氧基]乙醇(4);利用甲磺酰氯将4的羟基转化为离去基团,再引入硫脲基团成功地合成了新型含硫脲基的酚醚类衍生物——2-[4-(3-吗啉丙氧基)苯氧基]乙基异硫脲,其结构经1H NMR,13C NMR和MS表征.
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