Eight quinazoline derivatives(8a ~8h) were designed and synthesized from 3-hydroxy-4-methoxy benzaldehyde. The structures were confirmed by 1H NMR,13C NMR and MS. Preliminary antitumor activities test indicated that 8a ~8h exhibited potent antitumor activities against Bcap-37.%以异香草醛为原料,设计并合成了8个喹唑啉类衍生物(8a ~8h),其结构经1H NMR,13C NMR和MS确证.初步抗肿瘤活性测试结果表明,8a~8h对人乳腺癌细胞Bcap-37具有一定程度的体外活性抑制作用.
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