早孕纸条同时检测血和尿HCG在妇女急腹症鉴别诊断中的应用

摘要

Objective To evaluate the application significance of pregnancy test strip for the simultaneous detection of serum and urine human chorionic gonadotrophin (HCG) in the diagnosis of ectopic pregnancy (EP) in woman acute abdomen.Methods A total of 362 cases diagnosed as EP in patients with woman acute abdomen and 308 non-pregnant patients with woman acute abdomen were enrolled.Their serum and urine samples were collected.The samples were detected for serum and urine HCG by pregnancy test strip.The performance results of the single detection of serum or urine HCG and the simultaneous detection of serum and urine HCG were compared and analyzed.Results In woman acute abdomen,the sensitivity of the simultaneous detection of serum and urine HCG was 100％,which was obviously higher than that of the single detection of urine HCG (73.2％,P ＜ 0.01),and there was no statistical significance with that of the single detection of serum HCG (P ＞ 0.05).When the results for serum and urine HCG were all positive,the positive predictive value for the diagnosis of EP was 100％.When the results for serum and urine HCG were all negative,the negative predictive value for the diagnosis of EP was 100％.Conclusions In the differential diagnosis of woman acute abdomen,the simultaneous detection of serum and urine HCG by pregnancy test strip could improve the detection rate of EP,and could make up for the insufficiency of single detection of serum or urine HCG effectively.It has convenience and reasonable price,and is suitable for the hospitals without the quantitation detection of serum HCG.%目的 评估早孕纸条同时检测血清和尿人绒毛膜促性腺激素(HCG)在妇女急腹症中对异位妊娠(EP)鉴别诊断的应用价值.方法 收集362例明确诊断为EP的妇女急腹症患者及308例女性非妊娠急腹症患者的血清和尿液,分别用早孕纸条检测血清和尿HCG,对用早孕纸条单一检测血清或尿HCG与同时检测血清和尿HCG对EP的诊断性能进行比较分析.结果 在妇女急腹症时,用早孕纸条同时检测血清和尿液HCG诊断EP的敏感性为100％,明显高于单一检测尿HCG(73.2％,P＜0.01),与单一检测血清HCG差异无统计学意义(P＞0.05).血清和尿液同时阳性时诊断EP的阳性预测值为100％,同时阴性时诊断EP的阴性预测值为100％.结论 用早孕纸条同时检测血清和尿液HCG,在鉴别诊断妇女急腹症时可提高EP的检出率,能有效弥补单一用早孕纸条检测血清或尿HCG的不足,简捷价廉,值得在不具备定量检测血清HCG条件的医院推广应用.