Synthesis characterization molecular docking studies and biological evaluation of some novel hybrids based on quinazolinone benzofuran and imidazolium moieties as potential cytotoxic and antimicrobial agents

摘要

Objective(s):Hybridization of bioactive natural and synthetic compounds is one of the most promising novel approaches for the design of hit and lead compounds with new molecular structures. In this investigation, a series of novel hybrid structures bearing quinazolinone, benzofuran and imidazolium moieties were designed and synthesized.