Apatinib has anti-tumor effects and induces autophagy in colon cancer cells

机译：阿帕替尼具有抗肿瘤作用并诱导结肠癌细胞自噬

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Objective(s):Apatinib recently has been used to treat patients with gastric cancer, but the function of apatinib in colon cancer remains unclear. This study was conducted to investigate the impacts of apatinib on the biological function and its potential mechanism of colon cancer cells in vitro.

机译：目的：阿帕替尼最近已用于治疗胃癌患者，但阿帕替尼在结肠癌中的功能尚不清楚。本研究旨在探讨阿帕替尼在体外对结肠癌细胞的生物学功能及其潜在机制的影响。

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期刊名称 Iranian Journal of Basic Medical Sciences
作者
Wu Lu; He Ke; Ding Qianshan; Wang Zhen; Xiang Guoan; Yu Honggang;
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作者单位

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年(卷),期 2017(20),9
年度 2017
页码 990–995
总页数 6
原文格式 PDF
正文语种
中图分类
关键词
Apatinib Apoptosis Autophagy Colon cancer Migration mTOR;

机译：阿帕替尼;细胞凋亡;自噬;结肠癌;迁移;mTOR;

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专利

1. APATINIB HAS ANTI-TUMOR EFFECTS AND INDUCES AUTOPHAGY IN COLON CANCER CELLS [J] . LU WU, KE HE, QIANSHAN DING, Iranian Journal of Basic Medical Sciences . 2017,第9期

机译：阿帕替尼在结肠癌细胞中具有抗肿瘤作用并诱导自噬
2. Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation [J] . Zuzana Tylichová, Nicol Straková, Jan Vondrá?ek, The Journal of Nutritional Biochemistry . 2017,第期

机译：激活自噬和PPARγ保护结肠癌细胞免受丁酸酯和DHA的互动效应诱导的细胞类型依赖性方式：细胞分化的作用
3. Activation of autophagy and PPAR gamma protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation [J] . Tylichova Zuzana, Strakova Nicol, Vondracek Jan, The Journal of Nutritional Biochemistry . 2017,第期

机译：激活自噬和PPARγ以细胞类型依赖性方式通过丁酸酯和DHA的互动效应来保护结肠癌细胞免受诱导的凋亡：细胞分化的作用
4. Autophagy Inhibition Promotes HDACI-induced Apoptosis in MCF-7 Breast Cancer Cells [C] . Shimiao Wang, Xiaohui Li, Zhilong Xiu Chinese International Peptide Symposium . 2013

机译：自噬抑制促进HDACI诱导的MCF-7乳腺癌细胞凋亡
5. (S)-trifluoroselenomethionine, a new non-natural amino acid with enhanced methioninase-induced cytotoxicity toward human colon cancer cells. [D] . Lodge, Stephene Nathele. 2013

机译：（S）-三氟硒代蛋氨酸，一种新的非天然氨基酸，具有增强的蛋氨酸酶诱导的对人结肠癌细胞的细胞毒性。
6. ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells [O] . Adriana Celesia, Ornella Morana, Tiziana Fiore, 2020

机译：ROS依赖性的ER应激和自噬介导Tributyltin（IV）筛选在结肠癌细胞中的抗肿瘤作用
7. ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells [O] . Adriana Celesia, Ornella Morana, Tiziana Fiore, 2020

机译：ROS依赖性的ER应激和自噬介导Tributyltin（IV）筛选在结肠癌细胞中的抗肿瘤作用

Apatinib has anti-tumor effects and induces autophagy in colon cancer cells

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