Neuroprotection of a sesamin derivative 1 2-bis (3-methoxyphenyl) methyl ethane-1 2-dicaroxylic acid (MMEDA) against ischemic and hypoxic neuronal injury

摘要

Objective(s):Stroke may cause severe neuronal damage. The sesamin have been demonstrated to possess neuroprotection by its antioxidant and anti-inflammatory properties. One sesamin derivative was artificially composited, 1, 2-bis [(3-methoxyphenyl) methyl] ethane-1, 2-dicaroxylic acid (MMEDA) had been developed to study its antioxidative activity and neuroprotection.