摘要:<正> Introduction Pain is the most common reason for patients (1 in 5) seeking medical consultation. The most common pain conditions include osteo-arthritis (4-6%), rheumatoid arthritis (1%), lower back pain (5%), nerve injury pain (1-2%), migraine (12%) and post-operative pain (70 Million surgeries in 2000). Most patients do not get adequate pain relief because of poor choice of drugs and dose limiting side effects (opioids, NSAIDs, gabapentin,