DIHYDROPYRANS BY CYCLOADDITIONS OF OXADIENES

摘要

Among the most common types of hetero-Diels-Alder reaction is the formation of dihydropyrans by a [4 + 2] process involving a carbonyl group acting either as a dienophile or as part of a heterodienic framework. These two complementary versions of the oxa-Diels-Alder reaction (ODA) have created opportunities for the regio-, diastereo-, and enantiocontrolled access to natural products and bioactive molecules, including important carbohydrate derivatives, given the presence of tetrahydropyran frameworks in such compounds.