Studies on batch formulation of a kit for the preparation of the Tc-99m-Ubiquicidin (29-41): An infection imaging agent

摘要

The aim of this study was to formulate an indigenous cold kit of Ubiquicidin, UBI (29-41), for easy preparation of Tc-99m-UBI (29-41) to be used as an infection imaging agent A two component kit with the peptide and SnCl2 as vial 1 and optimum amount of NaOH as vial 2 was successfully formulated as seen from the consistent radiochemical and pharmaceutical purity of the product over six consecutive batches of kits. The utility of the kit could be demonstrated through in-vitro and in vivo specificity of Tc-99m-UBI (29-41). (C) 2015 Elsevier Ltd. All rights reserved.