摘要:目的 探究与分析自拟益气消囊汤治疗卵巢囊肿的作用机制及临床疗效.方法 选取我院自2012年11月至2014年11月收治的80例卵巢囊肿患者作为研究对象,采取随机数字表法分为对照组与观察组,每组各40例,对照组给予桂枝茯苓胶囊治疗,观察组给予自拟益气消囊汤治疗,对比两组患者的临床疗效、囊肿大小及激素水平.结果 对照组总有效率为77.50%,观察组总有效率为95.00%,组间相比具有显著差异(x2=5.46,P<0.05).对照组治疗前后囊肿大小相比具有显著差异(t=2.56,P<0.05);试验治疗前后囊肿大小相比差异有统计学意义(t=4.89,P< 0.05);对照组与观察组治疗后囊肿大小相比差异有统计学意义(t=3.45,P<0.05).对照组治疗前后血浆促卵泡激素、孕酮及雌二醇水平相比差异有统计学意义(t=2.34,P<0.05;t=2.99,P< 0.05;t=3.24,P<0.05).观察组治疗前后血浆促卵泡激素、孕酮及雌二醇水平相比差异有统计学意义(t=2.98,P<0.05;t=3.45,P<0.05;t=3.88,P<0.05).对照组治疗后与观察组治疗后血浆促卵泡激素、孕酮及雌二醇水平相比差异有统计学意义(t=2.55,P<0.05;t=2.78,P<0.05;t=3.11,P<0.05).结论 采用自拟益气消囊汤治疗卵巢囊肿的临床疗效显著,治疗后囊肿明显变小,激素水平改善,临床应用价值突出,值得广泛推广.%Objective To investigate action mechanism and clinical curative effect of self-made Yiqi Xiaonang soup in the treatment of ovarian cyst.Methods 80 cases of ovarian cyst in our hospital from November 2012 to November 2014 were selected and divided into control group and observation group according to random number table,40 cases in each group.Control group was given cassia twig tuckahoe capsule,while observation group was given self-made Yiqi Xiaonang soup.Clinical efficacy,the size of cyst and hormone levels were compared between two groups.Results The total effective rate of control group was 77.50%,that of observation group was 95.00%,with statistically significant difference between two groups (x 2=5.46,P<0.05).There was statistically significant difference in the size of cyst before and after treatment in control group and observation group (t=2.56,4.89;P<0.05),there was statistically significant difference in the size of cyst after treatment between two groups (t=3.45,P<0.05).There were statistically significant differences in the levels of serum follicle-stimulating hormone,progesterone and estradiol before and after treatment in control group and observation group (t=2.34,2.99,3.24,P<0.05;t=-2.98,3.45,3.88,P<0.05),there were statistically significant differences in the levels of serum follicle-stimulating hormone,progesterone and estradiol after treatment between two groups (t=2.55,2.78,3.11;P<0.05).Conclusion The clinical curative effect of self-made Yiqi Xiaonang soup in the treatment of ovarian cyst is significant,with ovarian cyst shrunken and hormone levels improved after treatment,worthy of clinical application.