摘要:Objective:Analysis of clinical characteristics of aged patients with femoral neck fracture inflammatory markers in peri oper-ation period, to explore the corresponding prevention strategies.Methods: Collected in our hospital from 2013 January to 2014 June in our hospital of elderly patients with femoral neck fracture as the research object, such as target detection for the obtained temperature,TNF-αand other information, Comparative analysis of admission,preoperative and postoperative .Resul ts:Within 24 hours of admis-sion, 1 days before operation and on postoperative day 2, three time around basic index during surgery:body temperature, pulse, respira-tion, white blood cell (WBC) count changed significantly (P 0.05), more than the comparison between groups was statistically significant ( P0.05), compared to more than between group, the differences were statistically significant (P0.05).Conclusion:By 2 hit trauma and surgical in elderly patients with femoral neck fracture, make the patient based signs (body temperature, pulse, respiration, WBC count) and serological markers of inflammation (CRP, HMGB-1, TNF-α, IL-6) appeared different degree of fluctuation.Through the damage control to reduce the postoperative inflammatory reaction imbalance rate, improve the quality of postoperative rehabilitation.%目的:分析高龄患者股骨颈骨折围手术期炎症指标的临床特征,探寻相应的预防策略. 方法:收集我院2013年1月~2014年6月我院高龄患者股骨颈骨折为研究对象,获得如体温、TNF-α及其他信息进行目标性检测,分析入院时、术前及术后之间的对比. 结果:入院24小时、术前1天和术后2天,3个时段围手术期基础指标:体温、脉搏、呼吸、白细胞( WBC)计数均有明显变化(P0.05),余组间比较均有统计学意义(P0 .05 ) ,余组间比较,差异均有统计学意义( P0.05). 结论:老年患者股骨颈骨折受到外伤和手术创伤的2次打击,使患者基础体征(体温、脉搏、呼吸、WBC计数)和血清学炎症指标( CRP、HMGB-1、TNF-α、IL-6 )出现不同程度波动. 通过损伤控制降低术后炎症反应失衡率,提高术后康复质量.