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An Adult Immunization Best Practices Learning Collaborative: Impact, Scale Up, and Spread

机译:成人免疫最佳实践学习合作:影响,扩大和传播

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The research objective was to rapidly scale up and spread a proven learning collaborative approach (intervention) for adult vaccination rates for influenza and pneumococcal disease from 7 to 39 US health care organizations and to examine improvement in adult immunization rates after scale-up. Comparative analyses were conducted between intervention and nonintervention propensity score-matched providers on vaccination rates using a difference-in-differences approach. Qualitative data, collected during site visits and in-person and virtual meetings, were used to enhance understanding of quantitative results. In 2017-2018, an analysis of a subset of sites (n = 9) from 2 intervention cohorts (similar to 20 sites each) demonstrated greater improvement than their matched providers in pneumococcal vaccinations (PV) for patients ages = 65 years (treatment effect range: 1.4%-3.7%, P 0.01) and PV for high-risk patients (eg, with immunocompromising conditions) aged 19-64 years (0.8%-1.6%, P 0.01). Significant effects were observed in one of the study cohorts for PV for at-risk patients (eg, with diabetes) aged 19-64 years (1.7%, P 0.01), and influenza vaccination rates (2.4%, P 0.001). Individual health systems demonstrated even greater improvements across all 4 vaccinations: 9.5% influenza; 8.7% PV ages = 65 years; 11.8% PV high-risk; 16.3% PV at-risk (all P 0.01). Results demonstrated that a 7-site pilot could be successfully scaled to 39 additional sites, with similar improvements in vaccination rates. Between 2014 and 2018, vaccination improvements among all 46 groups (7 pilot, 39 in subsequent cohorts) resulted in an estimated 5.5 million adult vaccinations administered or documented in 27 states.
机译:研究目标是为了迅速扩大和展开成人疫苗接种率为7至39名美国医疗组织的成人疫苗疾病的经过验证的学习协作方法(干预),并在扩大后审查成年免疫率的改善。使用差异差异差异方法,在干预和非行动倾销率匹配供应商之间进行比较分析。在现场访问和私人和虚拟会议期间收集的定性数据用于增强对定量结果的理解。 2017 - 2018年,从2个干预群(类似于20个站点)的站点(n = 9)的分析显示出比患者患者血管球体疫苗接种(PV)中的匹配提供者更高的改善> = 65岁(治疗效果范围:1.4%-3.7%,P <0.01)和高风险患者的光伏(例如,具有免疫造成条件)19-64岁(0.8%-1.6%,P <0.01)。在19-64岁患者的风险患者(例如糖尿病)的PV的一项研究队列中观察到显着影响(1.7%,P <0.01)和流感疫苗接种率(2.4%,P <0.001)。各个卫生系统在所有4个疫苗接种中表现出更大的改善:9.5%流感; 8.7%的光伏> = 65岁; 11.8%光伏高风险; 16.3%的普及风险(所有P <0.01)。结果表明,7位点飞行员可以成功扩展到39个其他地点,具有类似的疫苗接种率的改进。 2014年至2018年间,所有46次疫苗接种改善(7个试点,39中,后续队列)导致估计管理或记录了27个州的550万个成人疫苗。

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